For research use only
Product Infomation | |
Product Name | CC-90003 |
---|---|
CAS No. | 1621999-82-3 |
Molecular Weight | 458.44 |
Formula | C₂₂H₂₁F₃N₆O₂ |
SMILES | C=CC(NC1=CC(C)=CC=C1NC2=NC(NC3=CC(OC)=NC=C3C)=NC=C2C(F)(F)F)=O |
Stock status | Get quote |
Product description
Description | CC-90003 is an irreversible and selective inhibitor of ERK 1/2 with antitumor activity. | |
IC50 & Target | ________________________________________________________________________________________ ERK2 | |
In Vitro | _________________________________________________________________________________________ | |
Powder | -20°C | 3 years |
4°C | 2 years | |
In solvent | -80°C | 6 months |
-20°C | 1 month |
Peferences:
[1]. Monica M. Mita, et al. A phase Ia study of CC-90003, a selective extracellular signal-regulated kinase (ERK) inhibitor, in patients with relapsed or refractory BRAF or RAS-mutant tumors. Journal of Clinical Oncology 35, no. 15_suppl (May 20 2017) 2577-2577.